Subject Code: CY7L019 Subject Name: Structure and Function of Biomolecules L-T-P: 3-0-0 Credit: 3
Prerequisite(s): Nil
Carbohydrates: Ring and open chain structure of glucose and fructose. Reactions of glucose and fructose mutarotation. Inter conversion reactions- aldose to ketose, ketose to aldose, chain elongation and chain degradation, epimerization. Disaccharides: sucrose, Lactose, cellobiose, Reducing and non-reducing sugars, Polysaccharide: Starch, glycogen, Cellulose and Chitin, analysis of carbohydrates. Aminoacids, Proteins and nucleic acid: Proteins (structure and functions): Amino acids, structural features, optical activity, essential and non-essential amino acids, iso-electric point, synthesis and chemical properties of α amino acids. Peptides and it’s structure determination. Polypeptides or proteins: classifications, primary, secondary, tertiary and quaternary structure of proteins, glycoproteins, denaturation and folding, enzymes. Nucleic acids: Nitrogeneous base and pentose sugars, Nucleosides, nucleotides, Chemical and enzymatic hydrolysis, structure and functions of nucleic acids; DNA, RNA (m-RNA, t-RNA, r-RNA), an overview of gene expression (replication, transcription and translation), genetic code (origin, Wobble hypothesis and other important features), genetic errors, Central dogma, Protein synthesis.
Text/ Reference Books:
  1. Nelson D. L. and Cox M. M. Lehlinger Principles of Biochemistry, W. H. Freeman.
  2. Satyanarayan U. Biochemistry, New Central Book Agency.
  3. Stryer L.; Berg J. and Tymoczko J. L. Biochemistry, W. H. Freeman Publisher.
  4. LindhorstK. Essentials of Carbohydrate Chemistry and Biochemistry, Wiley.