Subject Code: CY7L021	Subject Name: Biophysical Chemistry	L-T-P: 3-0-0	Credit: 3
Prerequisite(s): Nil
Structures of biological macromolecules (proteins and polynucleic acids); Molecular Mechanics-simulating macromolecular structure; Spectroscopic methods to study structure of proteins and DNA; structural transitions in polypeptides, proteins and polynucleic acids. Interactions between macromolecules; Thermodynamics of protein folding/stability by fluorescence and circular dichroism techniques. Macromolecule-small molecule binding by biophysical methods.
Text/ Reference Books: Nall B. T. and Dill K. A Conformations and forces in protein Folding, American Association for the Advancement of science. Cantor C. R. and Schimmel P. R. Biophysical Chemistry Part-III, Freeman and Co. Gregory R. Protein solvent interactions, Marcel Dekker Inc.