Introduction to Biological Systems: Human body – Physiological aspects – Biothermofluidics: Renal System, Blood Circulation and Lungs – Heat Transfer and Temperature Distribution in the Human body – Mass, energy, and flow transport in biosystems and biotechnology – Biothermology: Major Challenges.
Thermal control: Cell – Cellular energy production – Energetics of Cell Growth and Division – Energetics of Body Metabolism – Body Temperature – Temperature Regulation – Pathologic Variations in Body Temperature.
Heat transfer modeling: A Bioheat Equation – The PennesBioheat Equation – Wulff Continuum Model – The Klinger Continuum Model – The Continuum Model by Chen and Holmes (1980) – Counter-current Heat Transfer: The Mitchel and Myers model – Model of Keller and Seiler – Weinbaum-Jiji Bioheat Transfer Models – Rhythms and Hemodynamic Parameters – porous medium approach to tissue and blood flow through capillaries.
Mass transfer modeling: mass diffusion in tissues – porous medium approach to bio mass transfer – lungs – Respiratory System – Alveolar Gas Transport – Lung Diffusing Capacity – Modeling Alveolar Gas Transport – Microscopic – macroscopic – unification – introduction to nephrology.
Applications: Extreme temperatures – Biothermal Cooling – freezing and thawing – Cryosurgery – Biothermal Heating – Radiofrequency thermotherapy – Thermal injury – modeling – lasers and tissue heating – Cell Surgery – Modeling of specific human body functions – measurement of thermophysical properties – transient bioheat equation modelling laser surgery in eye.
Recommended Books:
- Biomedical applications of heat and mass transfer, R. C. Seagrave, Iowa State University Press,(1971).
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