IIT Bhubaneswar Research group from School of Basic Sciences has published an article in Proteins: Structure, Function and Bioinformatics Journal

Dr. Ashis Biswas's research group from School of Basic Sciences has recently published a manuscript entitled “The impact of different mutations at arginine141 on the structure, subunit exchange dynamics and chaperone activity of Hsp16.3” in Proteins: Structure, Function and Bioinformatics journal (from Wiley publishers). This particular study identified an important amino acid residue (arginine141/R141) in C-terminal extension of Mycobacterium tuberculosis Hsp16.3 which efficiently controls its structure and chaperone function. Furthermore, the results presented in this article laid a good foundation for developing a better second generation vaccine candidate against tuberculosis.


Dr. Biswas is happy to announce that the cover image based on this article has recently been accepted for the Featured Cover of this journal (Vol. 88; Issue 6).